POLYCYSTIC OVARY SYNDROME-A LIFESTYLE RISK FACTOR OF MODERN WORLD
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Abstract
The polycystic ovary syndrome is a familial disorder, but the genetic basis of the syndrome remains controversial. Determining the mode of inheritance of this syndrome is difficult because there has been no clearly described male phenotype and because it is a disorder that affects principally women of reproductive age. There is a lack of information about further PCOS development and prognosis, considering the environmental and individual factors. No systematic studies were reported regarding the genetic integrity, especially the DNA damage in PCOS. Hence the present study was undertaken to evaluate a case study in Trivandrum Kerala district and the DNA damage in women with PCOS by investigating the biochemical and molecular cytogenetic alterations.
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