SYNTHESIS AND BIOLOGICAL ACTIVITY OF 1,2,3-TRIAZOLES BASED ON ACETELENE-CONTAINING CARBAMATE DERIVATIVES

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Published Jun 29, 2021
https://doi.org/10.17605/OSF.IO/Y7RC3
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Vol. 6 No. 2 (2021): VOLUME 6 ISSUE 2

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Yakubkhodzhaeva M. R
Tashkent State Dental Institute Tashkent city
Dzhuraev A. D
Tashkent State Dental Institute Tashkent city

Abstract

In this article, based on propargyl ethers, copper and silver acetylenides of propargyl ethers of carbamate derivatives were synthesized, and on their basis ɣ-iodopropargyl ethers of carbamates were synthesized. By studying the influence of various factors, the optimal conditions for their synthesis have been established. The pharmacological activity and toxicity of the synthesized compounds were studied. Compounds with high anti-inflammatory activity have been identified.

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How to Cite
[1]
Yakubkhodzhaeva M. R and Dzhuraev A. D, “SYNTHESIS AND BIOLOGICAL ACTIVITY OF 1,2,3-TRIAZOLES BASED ON ACETELENE-CONTAINING CARBAMATE DERIVATIVES”, IEJRD - International Multidisciplinary Journal, vol. 6, no. 2, p. 6, Jun. 2021.
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